Why Are We Hungry Despite Our Fat Reserves?
It is the fault of our brain that is accustomed to leptin, a protein secreted by adipose tissue that signals to the brain how much energy is stored in our body in the form of fat. The more we store fat, the higher the leptin level increases in the blood. But our brain gets used to an increased level of leptin and eventually considers it normal. In a way, it becomes “resistant” to leptin. It no longer hears anything and no longer realizes that it already has reserves of fat. In addition, our fatty adipose tissue secretes ghrenin, a hormone that stimulates appetite.